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Article

Genomic Profiling of Aggressive Thyroid Cancer in Association With its Clinicopathological Characteristics.

In vivo (Athens, Greece) - 1 Jan 2000

Kim Jae-Hui, Jeong Ji Yun, Seo An Na, Park Nora Jee-Young, Kim Moonsik, Park Ji Young

Abstract excerpt

BACKGROUND/AIM: Poorly differentiated thyroid carcinoma (PDTC), anaplastic thyroid carcinoma (ATC), and advanced DTC have poor outcomes. MATERIALS AND METHODS: We performed next-generation sequencing in nine selected aggressive thyroid cancers. RESULTS: Among the nine patients, the driver gene mutations BRAF V600E (3/9) and NRAS Q61K (1/9) were detected. Other oncogenic mutations included ERBB2 (1/9) and CDK4...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34972706
DOI: 10.21873/invivo.12682
PMCID: PMC8765130

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