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Article

Association Between Common Variants of APOE, ABCA7, A2M, BACE1, and Cerebrospinal Fluid Biomarkers in Alzheimer's Disease: Data from the PUMCH Dementia Cohort.

Journal of Alzheimer's disease : JAD - 1 Jan 2022

Dong Liling, Mao Chenhui, Liu Caiyan, Li Jie, Huang Xinying, Wang Jie, Lei Dan, Chu Shanshan, Sha Longze, Xu Qi, Peng Bin, Cui Liying, Gao Jing

Abstract excerpt

BACKGROUND: The previous studies have identified several genes in relation to Alzheimer's disease (AD), such as ABCA7, CR1, etc. A few studies have explored the association between the common variants, mainly in the non-coding regions of these genes, and cerebrospinal fluid (CSF) biomarkers. Fewer studies target the variants in the coding regions. OBJECTIVE: To illustrate the association between the common...

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PMID: 34958020
DOI: 10.3233/JAD-215067
PMCID: PMC8925115

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