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Article

Impact of NK Cell Activating Receptor Gene Variants on Receptor Expression and Outcome of Immunotherapy in Acute Myeloid Leukemia.

Frontiers in immunology - 1 Jan 2021

Hussein Brwa Ali, Hallner Alexander, Wennström Lovisa, Brune Mats, Martner Anna, Hellstrand Kristoffer, Bernson Elin, Thorén Fredrik B

Abstract excerpt

Natural killer cells are important effector cells in the immune response against myeloid malignancies. Previous studies show that the expression of activating NK cell receptors is pivotal for efficient recognition of blasts from patients with acute myeloid leukemia (AML) and that high expression levels impact favorably on patient survival. This study investigated the potential impact of activating receptor gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34956230
DOI: 10.3389/fimmu.2021.796072
PMCID: PMC8695486

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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