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Article

NK cell genotype and phenotype at diagnosis of acute lymphoblastic leukemia correlate with postinduction residual disease.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Dec 2014

Sullivan Erin M, Jeha Sima, Kang Guolian, Cheng Cheng, Rooney Barbara, Holladay Martha, Bari Rafijul, Schell Sarah, Tuggle MaCal, Pui Ching-Hon, Leung Wing

Abstract excerpt

PURPOSE: Not all natural killer (NK) cells are equally cytotoxic against leukemia because of differences in receptor gene content and surface expression. We correlated NK cell genotype and phenotype at diagnosis of childhood acute lymphoblastic leukemia (ALL) with minimal residual disease (MRD) after induction chemotherapy. EXPERIMENTAL DESIGN: The NK cells and leukemia blasts of 244 patients were analyzed at...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasm, Residual

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

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Source

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Identifiers

PMID: 25281696
DOI: 10.1158/1078-0432.CCR-14-0479
PMCID: PMC4252745

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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