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Natural killer receptor ligand expression on acute myeloid leukemia impacts survival and relapse after chemotherapy

15 Feb 2018

Abstract excerpt

Natural killer (NKs) cells provide rapid responses to viral-infected and malignant cells, including acute myeloid leukemia (AML) blasts. The balance among inhibitory and activating signals, delivered by multiple interactions between ligands on target cells and NK receptors, determines the posture of the NK cell response to either one of target cell elimination or tolerance. The aim of this work was to study the...

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PMID: 29449224
DOI: 10.1182/bloodadvances.2017015230

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