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Article

MARC1 p.A165T variant is associated with decreased markers of liver injury and enhanced antioxidant capacity in autoimmune hepatitis.

Scientific reports - 23 Dec 2021

Janik Maciej K, Smyk Wiktor, Kruk Beata, Szczepankiewicz Benedykt, Górnicka Barbara, Lebiedzińska-Arciszewska Magdalena, Potes Yaiza, Simões Inês C M, Weber Susanne N, Lammert Frank, Więckowski Mariusz R, Milkiewicz Piotr, Krawczyk Marcin

Abstract excerpt

The clinical picture of autoimmune hepatitis (AIH) varies markedly between patients, potentially due to genetic modifiers. The aim of this study was to evaluate genetic variants previously associated with fatty liver as potential modulators of the AIH phenotype. The study cohort comprised 313 non-transplanted adults with AIH. In all patients, the MARC1 (rs2642438), HSD17B13 (rs72613567), PNPLA3 (rs738409), TM6SF2...

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Share to Antioxidants
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Share to Polymorphism, Genetic
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Source

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Identifiers

PMID: 34949757
DOI: 10.1038/s41598-021-03521-3
PMCID: PMC8702547

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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