Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Carbonic anhydrase 9 confers resistance to ferroptosis/apoptosis in malignant mesothelioma under hypoxia

10 Aug 2019

Abstract excerpt

Hypoxia and acidity provide microenvironment for selection under evolutionary pressure and proliferation in cancer cells. Carbonic anhydrases (CAs) are a superfamily of metalloenzymes present in all life kingdoms, equilibrating the reactions among CO2, bicarbonate and H+. CA9, a membrane-associated α-CA, has been a drug target for various cancers. Whereas iron is essential not only for cancer cells but also for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Enzyme function and inhibition
Share to Peptidase Inhibition and Analysis

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 31442913
DOI: 10.1016/j.redox.2019.101297

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Carbonic anhydrase 9 confers resistance to ferroptosis/apoptosis in malignant mesothelioma under hypoxiaPMID 31442913Read ↗

Carbonic Anhydrase IX Inhibitors as Candidates for Combination Therapy of Solid TumorsSemantic proximity Read ↗

Ferroptosis Meets Cell–Cell ContactsSemantic proximity Read ↗

FMO4 drives lung adenocarcinoma by stabilizing the MAT2A/MAT2B complex and hindering ferroptosisSemantic proximity Read ↗

Asbestos conceives Fe(II)-dependent mutagenic stromal milieu through ceaseless macrophage ferroptosis and β-catenin induction in mesotheliumSemantic proximity Read ↗

Cancer-Associated Carbonic Anhydrases and Their InhibitionSemantic proximity Read ↗

Iron as spirit of life to share under monopolySemantic proximity Read ↗

Carbonic anhydrase related protein VIII and its role in neurodegeneration and cancer.Semantic proximity Read ↗

Impairment of carbonic anhydrase IX ectodomain cleavage reinforces tumorigenic and metastatic phenotype of cancer cells.Semantic proximity Read ↗

Acid-exposed and hypoxic cancer cells do not overlap but are interdependent for unsaturated fatty acid resourcesSemantic proximity Read ↗

Iron overload as a major targetable pathogenesis of asbestos-induced mesothelial carcinogenesisSemantic proximity Read ↗

Iron overload signature in chrysotile‐induced malignant mesotheliomaSemantic proximity Read ↗

Carbonic anhydrase VIII as a regulator of intracellular calcium signaling: mechanistic insights and implications in human disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.