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Article

Deciphering diffuse glioma immune microenvironment as a key to improving immunotherapy results.

Current opinion in oncology - 1 Nov 2022

Picca Alberto, Finocchiaro Gaetano

Abstract excerpt

PURPOSE OF REVIEW: Immunotherapeutic approaches have yet to demonstrate their clinical efficacy in diffuse gliomas. Evidence is mounting that the central nervous system is subject to immune surveillance, but brain tumours manage to escape due to factors intrinsic to their tumoral immune microenvironment (TME). This review aims to discuss the recently characterized molecular bases of the glioma TME and the...

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Brain Neoplasms
Glioma
Immunotherapy
Isocitrate Dehydrogenase
Mutation
Tumor Microenvironment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36000367
DOI: 10.1097/CCO.0000000000000895

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