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Article

Comparison of the Transcriptomic Signatures in Pediatric and Adult CML

14 Dec 2021

Abstract excerpt

Children with chronic myeloid leukemia (CML) tend to present with higher white blood counts and larger spleens than adults with CML, suggesting that the biology of pediatric and adult CML may differ. To investigate whether pediatric and adult CML have unique molecular characteristics, we studied the transcriptomic signature of pediatric and adult CML CD34+ cells and healthy pediatric and adult CD34+ control...

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PMID: 34944883
DOI: 10.3390/cancers13246263

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