A hybrid stochastic-deterministic approach to explore multiple infection and evolution in HIV.

Abstract excerpt

To study viral evolutionary processes within patients, mathematical models have been instrumental. Yet, the need for stochastic simulations of minority mutant dynamics can pose computational challenges, especially in heterogeneous systems where very large and very small sub-populations coexist. Here, we describe a hybrid stochastic-deterministic algorithm to simulate mutant evolution in large viral populations,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Algorithms
• Share to Cells
• Share to Computational Biology