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Article

Complementation and epistasis in viral coinfection dynamics.

Genetics - 1 May 2009

Gao Hong, Feldman Marcus W

Abstract excerpt

Coinfection in RNA virus populations results in two important phenomena, complementation and recombination. Of the two, complementation has a strong effect on selection against deleterious mutations, as has been confirmed in earlier studies. As complementation delays the purging of less-fit mutations, coinfection may be detrimental to the evolution of a virus population. Here we employ both deterministic modeling...

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Share to Epistasis, Genetic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Recombination, Genetic

Share to RNA Virus Infections

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Source

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Identifiers

PMID: 19270273
DOI: 10.1534/genetics.108.099796
PMCID: PMC2674821

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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