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Article

Multiploid Inheritance of HIV-1 during Cell-to-Cell Infection

4 May 2011

Abstract excerpt

During cell-to-cell transmission of human immunodeficiency virus type 1 (HIV-1), many viral particles can be simultaneously transferred from infected to uninfected CD4 T cells through structures called virological synapses (VS). Here we directly examine how cell-free and cell-to-cell infections differ from infections initiated with cell-free virus in the number of genetic copies that are transmitted from one...

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PMID: 21543479
DOI: 10.1128/jvi.00231-11

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