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Article

Associations between ALDOB polymorphisms and intrahepatic cholestasis of pregnancy susceptibility in the Chinese Han population.

Ginekologia polska - 1 Jan 2024

Liu Xianxian, Xin Siming, Zheng Jiusheng, Liu Huai, Zeng Yang, Wu Xiaoying, Zhang Feng, Zeng Xiaoming, Zou Yang, Lai Hua

Abstract excerpt

OBJECTIVES: To research the associations between fructose-bisphosphate aldolase B (ALDOB) gene polymorphisms and intrahepatic cholestasis of pregnancy (ICP) risk. MATERIAL AND METHODS: Whole-genome sequencing (WGS) was performed to detect ALDOB polymorphisms. Five web-available tools were employed to predict the effect of the site variant on the protein. Protein structure comparisons between the reference and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37743645
DOI: 10.5603/gpl.92931

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