Article
Prevalence of Germline Variants in Advanced Renal Cell Carcinoma in North India.
JCO global oncology - 1 Jul 2025
Nagpal Chitrakshi, Divakar Mohit Kumar, Baskarane Hemavathi, Tansir Ghazal, Jain Rishabh, Sharma Aparna, Sahoo Ranjit Kumar, Bakhshi Sameer, Gupta Ishaan, Minocha Shilpi, Kumar Saran, Tanwar Pranay, Nayak Brusabhanu, Nayyar Rishi, P Sridhar, Kaushal Seema, Ojha Sanjay, Nangla Parnika, Haresh Kunhi Parambath, Seth Amlesh, Batra Atul
Abstract excerpt
PURPOSE: Genetic predisposition plays an important role in the pathogenesis of renal cell carcinoma. The prevalence of pathogenic/likely pathogenic (P/LP) in patients with renal cell cancer (RCC) is highly variable, and close to 40% of these can be missed with the current testing guidelines. METHODS: This is a prospective study of all patients with metastatic RCC unselected for high-risk features, registered at...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.