Article
CCR5 and Biological Complexity: The Need for Data Integration and Educational Materials to Address Genetic/Biological Reductionism at the Interface of Ethical, Legal, and Social Implications.
Frontiers in immunology - 1 Jan 2021
Bauss Jacob, Morris Michele, Shankar Rama, Olivero Rosemary, Buck Leah N, Stenger Cynthia L, Hinds David, Mills Joshua, Eby Alexandra, Zagorski Joseph W, Smith Caitlin, Cline Sara, Hartog Nicholas L, Chen Bin, Huss John, Carcillo Joseph A, Rajasekaran Surender, Bupp Caleb P, Prokop Jeremy W
Abstract excerpt
In the age of genomics, public understanding of complex scientific knowledge is critical. To combat reductionistic views, it is necessary to generate and organize educational material and data that keep pace with advances in genomics. The view that CCR5 is solely the receptor for HIV gave rise to demand to remove the gene in patients to create host HIV resistance, underestimating the broader roles and complex...
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