Article
A brain-wide genome-wide association study of candidate quantitative trait loci associated with structural and functional phenotypes of pain sensitivity.
Cerebral cortex (New York, N.Y. : 1991) - 24 May 2023
Zhang Li, Pan Yiwen, Huang Gan, Liang Zhen, Li Linling, Zhang Min, Zhang Zhiguo
Abstract excerpt
Individual pain sensitivity is modulated by the brain's structural and functional features, but its heritability remains unclear. This paper conducted a brain-wide genome-wide association study (GWAS) to explore the genetic bases of neuroimage phenotypes of pain sensitivity. In total, 432 normal participants were divided into high and low pain sensitivity groups according to the laser quantitative test threshold....
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