Article
The Hippo Pathway Effectors YAP and TAZ Regulate LH Release by Pituitary Gonadotrope Cells in Mice.
Endocrinology - 1 Jan 2022
Lalonde-Larue Ariane, Boyer Alexandre, Dos Santos Esdras Corrêa, Boerboom Derek, Bernard Daniel J, Zamberlam Gustavo
Abstract excerpt
The Hippo transcriptional coactivators YAP and TAZ exert critical roles in morphogenesis, organ size determination and tumorigenesis in many tissues. Although Hippo kinase cascade activity was recently reported in the anterior pituitary gland in mice, the role of the Hippo effectors in regulating gonadotropin production remains unknown. The objective of this study was therefore to characterize the roles of YAP...
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