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Article

Development of an efficient Sanger sequencing-based assay for detecting SARS-CoV-2 spike mutations.

PloS one - 1 Jan 2021

Lim Ho Jae, Park Min Young, Jung Hye Soo, Kwon Youngjin, Kim Inhee, Kim Dong Kwan, Yu Nae, Sung Nackmoon, Lee Sun-Hwa, Park Jung Eun, Yang Yong-Jin

Abstract excerpt

Novel strains of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) harboring nucleotide changes (mutations) in the spike gene have emerged and are spreading rapidly. These mutations are associated with SARS-CoV-2 transmissibility, virulence, or resistance to some neutralizing antibodies. Thus, the accurate detection of spike mutants is crucial for controlling SARS-CoV-2 transmission and identifying...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Spike Glycoprotein, Coronavirus

Source

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Identifiers

PMID: 34905589
DOI: 10.1371/journal.pone.0260850
PMCID: PMC8670694

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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