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Article

Frequency distribution of HCV resistance-associated variants in infected patients treated with direct-acting antivirals.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Feb 2022

Cabral Bianca Catarina Azeredo, Ramos Juliene Antonio, Silveira Amanda Laryssa de Melo, Nascimento Érica Ramos Dos Santos, Ferreira Selma Baía, Coelho Henrique Sérgio Moraes, Moura-Neto Rodrigo Soares, Villela-Nogueira Cristiane Alves, Hoffmann Luísa, Silva Rosane

Abstract excerpt

BACKGROUND: Hepatitis C virus (HCV) is a global public health problem. Second-generation direct-acting antivirals targeting non-structural regions on the viral genome are the cornerstone for treatment of chronic infection. However, resistance-associated variants (RAVs) have been reported to be associated with therapeutic failure. The aim of this study was to assess the frequency of variants, including RAVs, in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34902582
DOI: 10.1016/j.ijid.2021.12.320

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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