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Article

Resistance-associated variants in HCV subtypes 1a and 1b detected by Ion Torrent sequencing platform.

Antiviral therapy - 1 Jan 2016

Gaspareto Karine V, Ribeiro Roberto M, de Mello Malta Fernanda, Gomes-Gouvêa Michele S, Muto Nair H, Romano Camila M, Mendes-Correa Maria C, Carrilho Flair J, Sabino Ester C, Rebello Pinho João R

Abstract excerpt

BACKGROUND: As a result of increased understanding of the HCV life cycle, a new generation of drugs known as direct-acting antivirals (DAAs) was developed and is constantly being improved. At baseline, HCV variants resistant to DAA therapy may pre-exist, increasing the likelihood of treatment failure. The aim of this study was to investigate the presence of resistance-associated variants (RAVs) in treatment-naive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27314166
DOI: 10.3851/IMP3057

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