Article
Naturally occurring NS3 resistance-associated variants in hepatitis C virus genotype 1: Their relevance for developing countries.
Virus research - 2 Sept 2016
Echeverría Natalia, Betancour Gabriela, Gámbaro Fabiana, Hernández Nelia, López Pablo, Chiodi Daniela, Sánchez Adriana, Boschi Susana, Fajardo Alvaro, Sóñora Martín, Moratorio Gonzalo, Cristina Juan, Moreno Pilar
Abstract excerpt
Hepatitis C virus (HCV) is a major cause of global morbidity and mortality, with an estimated 130-150 million infected individuals worldwide. HCV is a leading cause of chronic liver diseases including cirrhosis and hepatocellular carcinoma. Current treatment options in developing countries involve pegylated interferon-α and ribavirin as dual therapy or in combination with one or more direct-acting antiviral...
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