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Assessing causality between osteoarthritis with urate levels and gout: a bidirectional Mendelian randomization study.

Osteoarthritis and cartilage - 1 Apr 2022

Chen D, Xu H, Sun L, Li Y, Wang T, Li Y

Abstract excerpt

OBJECTIVES: The bidirectional association between osteoarthritis (OA) and urate levels and gout, though well-documented, is inconclusive. This Mendelian randomization (MR) study aims to examine the bidirectional causality between OA and urate levels as well as gout. METHODS: We used summary statistics data for serum urate levels from 288,649 CKDGen participants and gout from 69,374 Global Urate Genetics...

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Identifiers

PMID: 34896305
DOI: 10.1016/j.joca.2021.12.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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