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A link between mitotic defects and mitotic catastrophe: detection and cell fate

1 Dec 2021

Abstract excerpt

Although the phenomenon of mitotic catastrophe was first described more than 80 years ago, only recently has this term been used to explain a mechanism of cell death linked to delayed mitosis. Several mechanisms have been suggested for mitotic catastrophe development and cell fate. Depending on molecular perturbations, mitotic catastrophe can end in three types of cell death, namely apoptosis, necrosis, or...

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PMID: 34886882
DOI: 10.1186/s13062-021-00313-7

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