Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

First Report of the 3'-Untranslated Region +1506 (A>C) [NM_000518.5: c.*32A>C] mutation on the β-Globin Gene in the Indian Population.

Hemoglobin - 1 Sept 2021

Sen Aditi, Seenappa Venu, Chakrabarti Prantar, Dolai Tuphan Kanti

Abstract excerpt

The 3'-untranslated region (3'-UTR) is well known to be associated with the post-transcriptional regulation, because of the presence of important sequences that influence the fate of mRNA, and thus, in protein synthesis. The present study describes a point mutation on the β-globin 3'-UTR, +1506 (A>C) (HBB: c.*32A>C) in an Indian family during prenatal diagnosis (PND) screening of an at-risk couple. The members of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to beta-Globins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to beta-Thalassemia

Share to MicroRNAs

Share to Mutation

Share to Phenotype

Share to Pregnancy

Source

Identifiers

PMID: 34886762
DOI: 10.1080/03630269.2021.2011314

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

First Report of the 3'-Untranslated Region +1506 (A>C) [NM_000518.5: c.*32A>C] mutation on the β-Globin Gene in the Indian Population.PMID 34886762Read ↗

The +1,506 (A>C) mutation in the 3' untranslated region affects β-globin expression.Semantic proximity Read ↗

Identification of a novel mutation in the β-globin gene 3' untranslated region [+1,506 (A>C)] in a Japanese male with a heterozygous β-thalassemia phenotype.Semantic proximity Read ↗

Characterization of Two Deep Intronic Variants on the β-Globin Gene with Inconsistent Interpretations of Clinical Significance.Semantic proximity Read ↗

Identification of a Novel Mutation in the 3' Untranslated Region of the β-Globin Gene (HBB:c.*132C>G) in a Chinese Family.Semantic proximity Read ↗

Two Novel and Five Rare Mutations in the Non Coding Regions of the β-Globin Gene in the Iranian Population.Semantic proximity Read ↗

An insight of -50 (G>A) mutation in the direct repeat element of the β-globin gene: From Malaysian perspective.Semantic proximity Read ↗

Evaluation of the Function of a Rare Variant in the 3'-Untranslated Region of the β-Globin Gene.Semantic proximity Read ↗

Association in cis of the mutations +20 (C>T) in the 5' untranslated region and IVS-II-745 (C>G) on the β-globin gene.Semantic proximity Read ↗

Diseases and their clinical heterogeneity - Are we ignoring the SNiPers and micRomaNAgers? An illustration using Beta-thalassemia clinical spectrum and fetal hemoglobin levels.Semantic proximity Read ↗

In silico study on RNA structures of intronic mutations of beta-globin geneSemantic proximity Read ↗

β-Thalassemia Intermedia Caused by the β-Globin Gene 3' Untranslated Region: Another Case Report.Semantic proximity Read ↗

Two novel mutations in the 3' untranslated region of the beta-globin gene that are associated with the mild phenotype of beta thalassemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.