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Article

Evaluation of the Function of a Rare Variant in the 3'-Untranslated Region of the β-Globin Gene.

Hemoglobin - 1 Nov 2022

Targholi Sogol, Noormohammadi Zahra, Tafsiri Elham, Karimipoor Morteza

Abstract excerpt

β-Thalassemia (β-thal) is an inherited genetic disease that occurs because of the absence or reduction of β-globin chain synthesis. Genetic changes occur in different regions of the β-globin gene, but these mutations are less reported in the 3' untranslated region (3'-UTR). The objective of the present investigation was to evaluate the functional effect of a rare variant in the 3'-UTR of the β-globin gene. A...

Read the complete abstract on PubMed

Topics

Humans
3' Untranslated Regions
HEK293 Cells
Erythroid Cells
Mutation
beta-Globins

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Source

Identifiers

PMID: 36847660
DOI: 10.1080/03630269.2023.2167660

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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