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β-Thalassemia Intermedia Caused by the β-Globin Gene 3' Untranslated Region: Another Case Report.

Hemoglobin - 1 Mar 2022

Jiang Fan, Chen Gui-Lan, Li Jian, Tang Xue-Wei, Li Dong-Zhi

Abstract excerpt

The 3' untranslated region (3'UTR) is associated with mRNA stability because of its involvement in 3' end processing, polyadenylation, and mRNA capping. Mutations located in this area can cause a phenotype compatible with β+-thalassemia (β+-thal). We report a Chinese subject with β-thal intermedia (β-TI) who developed transfusion-dependent anemia. Molecular studies revealed that the patient was a compound...

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Identifiers

PMID: 35980111
DOI: 10.1080/03630269.2022.2086135

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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