Article
Genetic predisposition to Parkinson's disease and risk of cardio and cerebrovascular disease: a Mendelian randomization study.
Parkinsonism & related disorders - 1 Jan 2022
Wang Mengmeng, Zhang Zhizhong, Liu Dandan, Ji Lei, Huang Shuangjiao, Cao Liping, Wei Ning, Ye Dan, Ma Yazhou, Lian Xuegan
Abstract excerpt
BACKGROUND: Observational studies suggest that Parkinson's disease (PD) is related with the risk of cardio and cerebrovascular disease. However, the causality is not yet fully established. Therefore, we employed Mendelian randomization to assess whether PD is related to risk of ischemic stroke (IS), IS subtypes, coronary artery disease (CAD) and myocardial infarction (MI). METHODS: Eighty-eight and eleven single...
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