Article
Parkinson's Disease and Ischemic Stroke: a Bidirectional Mendelian Randomization Study.
Translational stroke research - 1 Aug 2022
Fang Shiyuan, Hu Xinzhi, Wang Tao, Yang Yutong, Xu Ran, Zhang Xiao, Luo Jichang, Ma Yan, Patel Aman B, Dmytriw Adam A, Jiao Liqun
Abstract excerpt
We aimed to assess the potential causal association between Parkinson's disease (PD) and ischemic stroke (IS) with Mendelian randomization methods. Summary statistics data from two large-scale genome-wide association studies (GWAS) for 33,674 PD cases and 40,585 IS cases were used in this study. We used inverse variance-weighted method for primary analysis, and four other Mendelian randomization methods (weighted...
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