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Article

Association between IL-6, miRNA-146a, MALAT1 genetic polymorphisms and risk of rheumatoid arthritis.

Personalized medicine - 1 Jan 2024

Ali Yasser Bm, Hasan Noura Ma, El-Maadawy Eman A, Bassyouni Iman H, El-Shahat Mohamed, Talaat Roba M

Abstract excerpt

Aim: This study aimed to investigate the associations between single nucleotide polymorphisms (SNPs) of IL-6 (-174G/C), microRNA146a (rs2910164C/G) and MALAT1 (rs619586A/G) and susceptibility to rheumatoid arthritis (RA) in Egyptians.Methods: SNPs were genotyped in 101 RA patients and 104 controls. Expression levels were evaluated either by Enzyme-linked immunosorbent assay (ELISA) for IL-6 or quantitative...

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PMID: 39263956
DOI: 10.1080/17410541.2024.2393072

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