Article
The IL-16 gene polymorphisms and the risk of the systemic lupus erythematosus.
Clinica chimica acta; international journal of clinical chemistry - 1 May 2009
Xue Hui, Gao Linbo, Wu Yongkang, Fang Wenliang, Wang Lanlan, Li Cui, Li Yi, Liang Weibo, Zhang Lin
Abstract excerpt
BACKGROUND: Interleukin 16 (IL-16) is an immunomodulatory cytokine which plays an important role in many inflammatory and autoimmune diseases. We determined the association between SNPs of IL-16 gene (i.e. rs11556218 G/T, rs4778889 C/T, and rs4072111 C/T) and systemic lupus erythematosus (SLE). METHODS: One hundred thirty-eight SLE patients and 199 controls were genotyped by polymerase chain reaction-restriction...
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