Article
Analysis of SARS-CoV-2 mutations associated with resistance to therapeutic monoclonal antibodies that emerge after treatment.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy - 1 Nov 2023
Focosi Daniele, McConnell Scott, Sullivan David J, Casadevall Arturo
Abstract excerpt
The mutation rate of the Omicron sublineage has led to baseline resistance against all previously authorized anti-Spike monoclonal antibodies (mAbs). Nevertheless, in case more antiviral mAbs will be authorized in the future, it is relevant to understand how frequently treatment-emergent resistance has emerged so far, under different combinations and in different patient subgroups. We report the results of a...
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