Article

SARS-CoV-2 Omicron Variants and Their Susceptibility Towards Monoclonal Antibodies in a Swedish Cohort During 2022-23, Studied by Next-Generation Sequencing

2023-09-12

Abstract excerpt

Monoclonal antibodies (mAbs) are an important treatment option for COVID-19 caused by SARS-CoV-2, especially in immunosuppressed patients. However, this treatment option can become ineffective due to mutations in the SARS-CoV-2 genome, mainly in the receptor binding domain (RBD) of the spike (S) protein. In the present study 7950 SARS-CoV-2 positive samples from the Uppsala and Örebro regions of central Sweden col...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f4475c7c-8791-5ae1-9a71-8320856c013a
DOI: 10.20944/preprints202309.0748.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

SARS-CoV-2 Omicron Variants and Their Susceptibility Towards Monoclonal Antibodies in a Swedish Cohort During 2022-23, Studied by Next-Generation SequencingDOI 10.20944/preprints202309.0748.v1Read

Dynamics of SARS-CoV-2 variants and mutations in Central Sweden between 2023 and 2024 and their potential implications on monoclonal antibodies pemivibart and sipavibart as PrEP in the region.Semantic proximity Read

Neutralization sensitivity of Omicron BA.2.75 to therapeutic monoclonal antibodiesSemantic proximity Read

In-Silico Analysis of Monoclonal Antibodies against SARS-CoV-2 Omicron.Semantic proximity Read

Revealing the threat of emerging SARS-CoV-2 mutations to antibody therapiesSemantic proximity Read

Revealing the Threat of Emerging SARS-CoV-2 Mutations to Antibody Therapies.Semantic proximity Read

Complete map of SARS-CoV-2 RBD mutations that escape the monoclonal antibody LY-CoV555 and its cocktail with LY-CoV016Semantic proximity Read

Production of a monoclonal antibody targeting the SARS-CoV-2 Omicron spike protein and analysis of SARS-CoV-2 Omicron mutations related to monoclonal antibody resistance.Semantic proximity Read

Evasion of neutralizing antibodies by Omicron sublineage BA.2.75Semantic proximity Read

Sotrovimab drives SARS-CoV-2 Omicron variant evolution in immunocompromised patientsSemantic proximity Read

Coronavirus Resistance Database (CoV-RDB): SARS-CoV-2 susceptibility to monoclonal antibodies, convalescent plasma, and plasma from vaccinated personsSemantic proximity Read

Host immunological responses facilitate development of SARS-CoV-2 mutations in patients receiving monoclonal antibody treatments.Semantic proximity Read

Variants of SARS CoV-2: mutations, transmissibility, virulence, drug resistance, and antibody/vaccine sensitivity.Semantic proximity Read