Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IL‐22 and inflammation: Leukin' through a glass onion

14 Nov 2008

Abstract excerpt

IL-22 is a Th17 T-cell-associated cytokine that is highly expressed during chronic inflammation. IL-22 receptor expression is absent on immune cells, but is instead restricted to the tissues, providing signaling directionality from the immune system to the tissues. Through Stat3 signaling, IL-22 induces a variety of proliferative, anti-apoptotic, and anti-microbial pathways. IL-22 is bi-functional with both...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dermatology and Skin Diseases
Share to Psoriasis: Treatment and Pathogenesis
Share to Whipple's Disease and Interleukins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19016525
DOI: 10.1002/eji.200838655

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IL‐22 and inflammation: Leukin' through a glass onionPMID 19016525Read ↗

IL-22 Binding Protein (IL-22BP) in the Regulation of IL-22 BiologySemantic proximity Read ↗

A catch-22: Interleukin-22 and cancer.Semantic proximity Read ↗

The role of interleukin-22 in mammalian intestinal homeostasis; friend and foe.Semantic proximity Read ↗

Biological and pathological activities of interleukin-22Semantic proximity Read ↗

Clinical importance of IL-22 cascade in IBD.Semantic proximity Read ↗

An overview of IL-17 function and signalingSemantic proximity Read ↗

The IL-23/IL-17 pathway in human chronic inflammatory diseases—new insight from genetics and targeted therapiesSemantic proximity Read ↗

IL-17 family: Cytokines, receptors and signalingSemantic proximity Read ↗

IL-17 receptor–based signaling and implications for diseaseSemantic proximity Read ↗

IL-17F: Regulation, signaling and function in inflammationSemantic proximity Read ↗

Aberrant expression of interleukin‐22 and its targeting micro<scp>RNA</scp>s in oral lichen planus: a preliminary studySemantic proximity Read ↗

IL-22 Inhibits Epidermal Differentiation and Induces Proinflammatory Gene Expression and Migration of Human KeratinocytesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.