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Article

Modifying effects of TNF-α, IL-6 and VDR genes on the development risk and the course of COVID-19. Pilot study.

Drug metabolism and personalized therapy - 6 Dec 2021

Fishchuk Liliia, Rossokha Zoia, Pokhylko Valeriy, Cherniavska Yuliia, Tsvirenko Svitlana, Kovtun Serhii, Medvedieva Nataliia, Vershyhora Viktoriia, Gorovenko Nataliia

Abstract excerpt

OBJECTIVES: COVID-19 continues to range around the world and set morbidity and mortality antirecords. Determining the role of genetic factors in the development of COVID-19 may contribute to the understanding of the pathogenetic mechanisms that lead to the development of complications and fatalities in this disease. The aim of our study was to analyze the effect of TNF-α (rs1800629), IL-6 (rs1800795) and VDR...

Topics

COVID-19
Case-Control Studies
Genetic Predisposition to Disease
Genotype
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Interleukin-6

Pilot Projects

Polymorphism, Single Nucleotide

Receptors, Calcitriol

Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 34860474
DOI: 10.1515/dmpt-2021-0127

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-34860474-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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