The scaffold protein menin is essential for activating the MYC locus and MYC‐mediated androgen receptor transcription in androgen receptor‐dependent prostate cancer cells

Abstract excerpt

Dear Editor, The proto-oncogene MYC has a well-documented role in driving androgen receptor (AR) oncogenic functions in prostate cancer (PCa cells) [1] and was recently reported as a key activator in the regulation of AR transcription [2]. Dissecting the mechanisms underlying MYC-mediated AR regulation may be crucial for better understanding PCa development and improving its management. We recently demonstrated...

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