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The SARS-CoV-2 RNA polymerase is a viral RNA capping enzyme

8 Nov 2021

Abstract excerpt

SARS-CoV-2 is a positive-sense RNA virus responsible for the Coronavirus Disease 2019 (COVID-19) pandemic, which continues to cause significant morbidity, mortality and economic strain. SARS-CoV-2 can cause severe respiratory disease and death in humans, highlighting the need for effective antiviral therapies. The RNA synthesis machinery of SARS-CoV-2 is an ideal drug target and consists of non-structural protein...

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PMID: 34850141
DOI: 10.1093/nar/gkab1160

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