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Article

Genome-Wide Gene-Sodium Interaction Analyses on Blood Pressure: The Genetic Epidemiology Network of Salt-Sensitivity Study.

Hypertension (Dallas, Tex. : 1979) - 1 Aug 2016

Li Changwei, He Jiang, Chen Jing, Zhao Jinying, Gu Dongfeng, Hixson James E, Rao Dabeeru C, Jaquish Cashell E, Gu Charles C, Chen Jichun, Huang Jianfeng, Chen Shufeng, Kelly Tanika N

Abstract excerpt

We performed genome-wide analyses to identify genomic loci that interact with sodium to influence blood pressure (BP) using single-marker-based (1 and 2 df joint tests) and gene-based tests among 1876 Chinese participants of the Genetic Epidemiology Network of Salt-Sensitivity (GenSalt) study. Among GenSalt participants, the average of 3 urine samples was used to estimate sodium excretion. Nine BP measurements...

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Identifiers

PMID: 27271309
DOI: 10.1161/HYPERTENSIONAHA.115.06765
PMCID: PMC5373034

Genes

CLGN
SCOC
ARHGAP42
CASP4
EPHA6
MKNK1
UST

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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