Article
DAZAP1, an hnRNP protein, is required for normal growth and spermatogenesis in mice.
RNA (New York, N.Y.) - 1 Sept 2008
Hsu Lea Chia-Ling, Chen Hsiang-Ying, Lin Yi-Wen, Chu Wei-Chen, Lin Ming-Jyun, Yan Yu-Ting, Yen Pauline H
Abstract excerpt
DAZAP1 (Deleted in Azoospermia Associated Protein 1) is a ubiquitous hnRNP protein that is expressed most abundantly in the testis. Its ability to shuttle between the nucleus and the cytoplasm and its exclusion from the transcriptionally inactive XY body in pachytene spermatocytes implicate it in mRNA transcription and transport. We generated Dazap1 mutant alleles to study the role of DAZAP1 in mouse development....
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