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Expression of Transcription Factor GATA-4 during Human Testicular Development and Disease<sup>1</sup>

1 Oct 2000

Abstract excerpt

GATA-4 is a highly conserved transcription factor that plays a critical role in regulating embryonic morphogenesis and cellular differentiation. Given the emerging role of GATA-4 in the development and function of murine gonads, we have now studied its role in human testis. We find that GATA-4 is expressed from early human fetal testicular development to adulthood. This transcription factor is evident in Sertoli...

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PMID: 11061558
DOI: 10.1210/jcem.85.10.6900

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