Association between TBXT rs2305089 polymorphism and chordoma in Iranian patients identified by a developed T-ARMS-PCR assay.

doi:10.1002/jcla.24150

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Association between TBXT rs2305089 polymorphism and chordoma in Iranian patients identified by a developed T-ARMS-PCR assay.

Journal of clinical laboratory analysis - 1 Jan 2022

Jalessi Maryam, Gholami Mohammad Saeed, Razmara Ehsan, Hassanzadeh Sajad, Sadeghipour Alireza, Jahanbakhshi Amin, Tabibkhooei Alireza, Bahrami Eshagh, Falah Masoumeh

Abstract excerpt

BACKGROUND: Chordoma is a locally aggressive bone tumor with a high capability of recurrence. Because chordoma often occurs at critical locations next to neurovascular structures, there is an urgent need to introduce validated biomarkers. T-box transcription factor T (TBXT; OMIM: 601397) plays an important role in the pathogenesis and survival of chordoma cells. METHODS: Herein, we aimed to show whether rs2305089...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Biomarkers, Tumor

Share to Bone Neoplasms

Share to Brachyury Protein

Share to Case-Control Studies

Share to Fetal Proteins

Share to T-Box Domain Proteins

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 34837714
DOI: 10.1002/jcla.24150
PMCID: PMC8761424

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between TBXT rs2305089 polymorphism and chordoma in Iranian patients identified by a developed T-ARMS-PCR assay.PMID 34837714Read ↗

A common single-nucleotide variant in T is strongly associated with chordoma.Semantic proximity Read ↗

Genomic profiles and clinical presentation of chordoma.Semantic proximity Read ↗

Genomic and transcriptomic characterization of skull base chordomaSemantic proximity Read ↗

The mutational landscape of skull base and spinal chordomas and the identification of potential prognostic and theranostic biomarkersSemantic proximity Read ↗

The mutational landscape of spinal chordomas and their sensitive detection using circulating tumor DNASemantic proximity Read ↗

Genome-wide DNA methylation profiling of recurrent and non-recurrent chordomasSemantic proximity Read ↗

TP53 Mutations as Drivers of Chordoma Progression and Hallmarks of Aggressive ChordomaSemantic proximity Read ↗

Unraveling molecular advancements in chordoma tumorigenesis and treatment response: a review of scientific discoveries and clinical implicationsSemantic proximity Read ↗

Genomic aberrations frequently alter chromatin regulatory genes in chordoma.Semantic proximity Read ↗

Emerging target discovery and drug repurposing opportunities in chordomaSemantic proximity Read ↗

T gene isoform expression pattern is significantly different between chordomas and notochords.Semantic proximity Read ↗

From Histology to Multi-Omics: Review of Chordoma Classification and Its Clinical ImplicationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.