Article
T gene isoform expression pattern is significantly different between chordomas and notochords.
Biochemical and biophysical research communications - 13 Nov 2015
Wang Ke, Hu Qingtao, Wang Liang, Chen Wei, Tian Kaibing, Cao Chunwei, Wu Zhen, Jia Guijun, Zhang Liwei, Zeng Changqing, Zhang Junting
Abstract excerpt
The T gene plays a key role in chordoma pathology. To investigate the role of T gene isoforms in chordoma, 22 skull base chordomas, three chordoma cell lines and 9 infant notochords, which were used as normal controls, were collected. We first conducted droplet digital PCR to quantify the absolute expression levels of the long and short isoforms of the T gene (T-long and T-short, respectively) and revealed that...
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