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UMOD Polymorphisms Associated with Kidney Function, Serum Uromodulin and Risk of Mortality among Patients with Chronic Kidney Disease, Results from the C-STRIDE Study.

Genes - 23 Oct 2021

Wang Jinwei, Liu Lili, He Kevin, Gao Bixia, Wang Fang, Zhao Minghui, Zhang Luxia, On Behalf Of The Chinese Cohort Study Of Chronic Kidney Disease C-Stride

Abstract excerpt

We aimed to explore associations of several single nucleotide polymorphisms (SNPs) detected by genome-wide association studies in uromodulin (UMOD) gene with phenotypes and prognosis of chronic kidney disease (CKD) among 2731 Chinese patients with CKD stage 1-4. Polymorphisms of rs11864909, rs4293393, rs6497476, and rs13333226 were genotyped using the Sequenom MassARRAY iPLEX platform. The SNPs of rs13333226 and...

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PMID: 34828293
DOI: 10.3390/genes12111687
PMCID: PMC8620616

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