Article
The value of uromodulin as a new serum marker to predict decline in renal function.
Journal of hypertension - 1 Jan 2018
Leiherer Andreas, Muendlein Axel, Saely Christoph H, Brandtner Eva M, Geiger Kathrin, Fraunberger Peter, Drexel Heinz
Abstract excerpt
BACKGROUND: Uromodulin is the most abundant protein in urine. Low uromodulin has been found associated with diabetes as well as with chronic kidney disease (CKD). Whether it also predicts a future decline in kidney function is not known. METHODS: We evaluated the association between serum uromodulin and kidney function in 529 patients and performed a genome-wide association study. Clinical parameters including...
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