Article
Plasmodium vivax Cysteine-Rich Protective Antigen Polymorphism at Exon-1 Shows Recombination and Signatures of Balancing Selection.
Genes - 28 Dec 2020
González-Cerón Lilia, Cebrián-Carmona José, Mesa-Valle Concepción M, García-Maroto Federico, Santillán-Valenzuela Frida, Garrido-Cardenas Jose Antonio
Abstract excerpt
Plasmodium vivax Cysteine-Rich Protective Antigen (CyRPA) is a merozoite protein participating in the parasite invasion of human reticulocytes. During natural P. vivax infection, antibody responses against PvCyRPA have been detected. In children, low anti-CyRPA antibody titers correlated with clinical protection, which suggests this protein as a potential vaccine candidate. This work analyzed the genetic and...
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