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Bioinformatic and cell-based tools for pooled CRISPR knockout screening in mosquitos

24 Nov 2021

Abstract excerpt

Mosquito-borne diseases present a worldwide public health burden. Current efforts to understand and counteract them have been aided by the use of cultured mosquito cells. Moreover, application in mammalian cells of forward genetic approaches such as CRISPR screens have identified essential genes and genes required for host-pathogen interactions, and in general, aided in functional annotation of genes. An...

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PMID: 34819517
DOI: 10.1038/s41467-021-27129-3

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