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Optimized CRISPR tools and site-directed transgenesis towards gene drive development in Culex quinquefasciatus mosquitoes

20 May 2021

Abstract excerpt

Culex mosquitoes are a global vector for multiple human and animal diseases, including West Nile virus, lymphatic filariasis, and avian malaria, posing a constant threat to public health, livestock, companion animals, and endangered birds. While rising insecticide resistance has threatened the control of Culex mosquitoes, advances in CRISPR genome-editing tools have fostered the development of alternative genetic...

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CRISPR and Genetic Engineering
Insect symbiosis and bacterial influences
Mosquito-borne diseases and control

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34017003
DOI: 10.1038/s41467-021-23239-0

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