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Article

Genetic alterations associated with malignant transformation of sporadic vestibular schwannoma.

Acta neurochirurgica - 1 Feb 2022

Håvik Aril Løge, Bruland Ove, Miletic Hrvoje, Poulsgaard Lars, Scheie David, Fugleholm Kåre, Lund-Johansen Morten, Knappskog Per-Morten

Abstract excerpt

INTRODUCTION: Malignant peripheral nerve sheath tumor of the vestibulocochlear nerve (VN-MPNST) is exceedingly rare and carries a poor prognosis. Little is known about its underlying genetics and in particular the process of malignant transformation. There is an ongoing debate on whether the transformation is initiated by ionizing radiation. We present here the analysis and comparison of two post-radiation...

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Identifiers

PMID: 34816314
DOI: 10.1007/s00701-021-05062-0
PMCID: PMC8854236

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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