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Article

In vivomicroevolution ofMycobacterium tuberculosisand transient emergence ofatpE_Ala63Pro mutation during treatment in a pre-XDR TB patient

18 Nov 2021

Abstract excerpt

This letter describes microevolution of a pre-XDR MTB strain isolated from a pulmonary TB patient over an 18-month exposure to BDQ. MDR-TB therapies with BDQ require a functional background regimen to prevent emergence of additional resistance.https://bit.ly/3D05qT9

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Identifiers

PMID: 34795042
DOI: 10.1183/13993003.02102-2021

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