Drug resistance evolution of a Mycobacterium tuberculosis strain from a noncompliant patient.

doi:10.1128/JCM.43.7.3114-3120.2005

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Article

Drug resistance evolution of a Mycobacterium tuberculosis strain from a noncompliant patient.

Journal of clinical microbiology - 1 Jul 2005

Meacci Francesca, Orrù Germano, Iona Elisabetta, Giannoni Federico, Piersimoni Claudio, Pozzi Gianni, Fattorini Lanfranco, Oggioni Marco R

Abstract excerpt

The emergence and spread of multidrug-resistant (MDR) Mycobacterium tuberculosis (MT) represents a worldwide health care problem because of the difficulty in treating these infections. Development of drug resistance in MT arises mainly by mutation of chromosomal genes. To investigate the evolution of a MT population during a long-lasting infection, the phenotypic and genotypic changes in the drug resistance of 10...

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Identifiers

PMID: 16000422
DOI: 10.1128/JCM.43.7.3114-3120.2005
PMCID: PMC1169130

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.