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Article

Congenital leptin and leptin receptor deficiencies in nine new families: identification of six novel variants and review of literature.

Molecular genetics and genomics : MGG - 1 Jul 2023

Mazen Inas H, El-Gammal Mona A, Elaidy Aya A, Anwar Ghada M, Ashaat Engy A, Abdel-Ghafar Sherif F, Abdel-Hamid Mohamed S

Abstract excerpt

Early childhood obesity is a real public health problem worldwide. Identifying the etiologies, especially treatable and preventable causes, can direct health professionals toward proper management. Measurement of serum leptin levels is helpful in the diagnosis of congenital leptin and leptin receptor deficiencies which are considered important rare causes of early childhood obesity. The main aim of this study was...

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PMID: 37140700
DOI: 10.1007/s00438-023-02025-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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